Dapatkah kopi melindungi terhadap melanoma ? --T-REC-komunitas reptil-semarang--KSE-komunitas satwa eksotik

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Dapatkah  kopi melindungi terhadap melanoma  ? 

studi epidemiologi dan pra - klinis telah menunjukkan bahwa konsumsi kopi memiliki efek perlindungan terhadap kanker kulit non-melanoma . Namun efek perlindungan untuk melanoma kulit ( ganas/malignant dan in situ ) kurang jelas , menurut sebuah studi baru ....read more

Can coffee
protect against malignant melanoma? Study looks at trends

Date:

January 20, 2015

Source:

Oxford University
Press USA

Summary:

Both epidemiological
and pre-clinical studies have suggested that coffee consumption has a
protective effect against non-melanoma skin cancers. However the protective
effect for cutaneous melanoma (malignant and in situ) is less clear, according
to a new study.

...............

both epidemiological and
pre-clinical studies have suggested that coffee consumption has a protective
effect against non-melanoma skin cancers. However the protective effect for
cutaneous melanoma (malignant and in situ) is less clear, according to a study
published January 20 in the JNCI: Journal of the National
Cancer Institute.

To determine if there is an association between coffee consumption and risk
of cutaneous melanoma, Erikka Loftfield, M.P.H., of the Division of Cancer
Epidemiology and Genetics, National Cancer Institute, and colleagues used data
from the NIH-AARP Diet and Health Study. Information on coffee consumption was
obtained from 447,357 non-Hispanic white subjects with a self-administered
food-frequency questionnaire in 1995/1996, with a median follow-up of 10 years.
All subjects included in the analysis were cancer-free at baseline, and the
authors adjusted for ambient residential ultraviolet radiation exposure, body
mass index, age, sex, physical activity, alcohol intake, and smoking history.

Overall, the highest coffee intake was inversely associated with a risk of
malignant melanoma, with a 20% lower risk for those who consumed 4 cups per day
or more. There was also a trend toward more protection with higher intake, with
the protective effect increasing from 1 or fewer cups to 4 or more. However,
the effect was statistically significant for caffeinated but not decaffeinated
coffee and only for protection against malignant melanoma but not melanoma
in-situ, which may have a different etiology.

The researchers point out that the results are preliminary and may not be
applicable to other populations, and therefore additional investigations of
coffee intake are needed. However, they conclude that "Because of its high
disease burden, lifestyle modifications with even modest protective effects may
have a meaningful impact on melanoma morbidity.







Story Source:

The above story is based on materials provided by Oxford
University Press USA.Note: Materials may be edited for content and length.

http://www.sciencedaily.com/releases/2015/01/150120185946.htm

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