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Otak anak-anak obesitas lebih responsif terhadap gula
Otak anak-anak obesitas secara harfiah menyala berbeda ketika mencicipi gula , sebuah studi baru menemukan . Rasa sense of "food reward" - yang melibatkan adanya termotivasi oleh makanan dan perasaan yang baik dari itu - bisa berarti beberapa anak memiliki circuitries otak yang mempengaruhi mereka untuk menginginkan lebih banyak gula sepanjang hidup , kata peneliti............read more
Obese children's
brains more responsive to sugar
Date:
December 12, 2014
Source:
University of
California, San Diego Health Sciences
Summary:
The brains of obese
children literally light up differently when tasting sugar, a new study has
found. This elevated sense of "food reward" -- which involves being
motivated by food and deriving a good feeling from it -- could mean some
children have brain circuitries that predispose them to crave more sugar
throughout life, researchers say.
..........................
A new study led by
researchers at University of California, San Diego School of Medicine finds
that the brains of obese children literally light up differently when tasting
sugar.
Published online in International Journal of Obesity, the study
does not show a causal relationship between sugar hypersensitivity and
overeating but it does support the idea that the growing number of America's
obese youth may have a heightened psychological reward response to food.
This elevated sense of "food reward" -- which involves being
motivated by food and deriving a good feeling from it -- could mean some
children have brain circuitries that predispose them to crave more sugar
throughout life.
"The take-home message is that obese children, compared to healthy
weight children, have enhanced responses in their brain to sugar," said
first author Kerri Boutelle, PhD, professor in the Department of Psychiatry and
founder of the university's Center for Health Eating and Activity Research
(CHEAR).
"That we can detect these brain differences in children as young as
eight years old is the most remarkable and clinically significant part of the
study," she said.
For the study, the UC San Diego team scanned the brains of 23 children,
ranging in age from 8 to 12, while they tasted one-fifth of a teaspoon of water
mixed with sucrose (table sugar). The children were directed to swirl the
sugar-water mix in the mouth with their eyes closed, while focusing on its
taste.
Ten of the children were obese and 13 had healthy weights, as classified by
their body mass indices. All had been pre-screened for factors that could
confound the results. For example, they were all right-handed and none suffered
from psychiatric disorders, such as anxiety or ADHD. They also all liked the
taste of sucrose.
The brain images showed that obese children had heightened activity in the
insular cortex and amygdala, regions of the brain involved in perception,
emotion, awareness, taste, motivation and reward.
Notably, the obese children did not show any heightened neuronal activity
in a third area of the brain -- the striatum -- that is also part of the
response-reward circuitry and whose activity has, in other studies, been
associated with obesity in adults.
The striatum, however, does not develop fully until adolescence. The
researchers said one of the interesting aspects of the study is that the brain
scans may be documenting, for the first time, the early development of the food
reward circuitry in pre-adolescents.
"Any obesity expert will tell you that losing weight is hard and that
the battle has to be won on the prevention side," said Boutelle, who is
also a clinical psychologist. "The study is a wake-up call that prevention
has to start very early because some children may be born with a hypersensitivity
to food rewards or they may be able to learn a relationship between food and
feeling better faster than other children."
According to studies, children who are obese have an 80 to 90 percent
chance of growing up to become obese adults. Currently about one in three
children in the U.S. is overweight or obese.
Story Source:
The above story is based on materials provided by University
of California, San Diego Health Sciences. Note: Materials may be edited for content
and length.
Journal Reference:
1. K Boutelle, C E Wierenga, A
Bischoff-Grethe, A J Melrose, E Grenesko-Stevens, M P Paulus, W H Kaye. Increased
brain response to appetitive tastes in the insula and amygdala in obese
compared to healthy weight children when sated. International
Journal of Obesity, 2014; DOI: 10.1038/ijo.2014.206