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budi pradana--berita artikel terkait tentang stomach acid,perut,asam lambung,lambung,sensors,voltaic
cell,cairan,asam,cairan asam,acidic fluids,gastrointestinal,batteries,battere, Insinyur
memanfaatkan asam lambung untuk daya sensor kecil
Insinyur memanfaatkan asam lambung untuk
daya sensor kecil
perangkat elektronik dimasukkan ke tubuh
yang bisa memantau kondisi fisiologis
atau memberikan obat
Tanggal:
6 Februari 2017
Sumber:
Institut Teknologi Massachusetts
Ringkasan:
Para peneliti telah merancang sel volta
kecil yang ditopang oleh cairan asam
di perut dan menghasilkan daya yang cukup
untuk menjalankan sensor atau
perangkat pengiriman obat yang dapat berada di
saluran pencernaan untuk
waktu yang dapat diperpanjang. jenis sumber bisa menawarkan alternatif
yang lebih aman dan
tahan lama dengan baterai tradisional sekarang untuk
digunakan pada daya perangkat tersebut.
......................
Para peneliti di MIT dan Brigham
and Women's Hospital telah merancang
dan menunjukkan sel volta kecil yang ditopang oleh cairan
asam di perut.
Sistem ini dapat menghasilkan daya yang cukup untuk menjalankan
sensor
kecil atau perangkat pengiriman obat yang dapat berada di saluran
pencernaan
untuk waktu yang lama.
para peneliti mengatakan , jenis sumber bisa menawarkan hal yang lebih
aman dan alternatif
lebih rendah-biaya daripada baterai
tradisional
sekarang yang digunakan untuk daya perangkat tersebut .
"Kita perlu menemukan cara-cara
untuk daya sistem ingestible untuk
waktu yang lama," kata Giovanni Traverso,
afiliasi penelitian di Koch
Institute for Integrative Cancer Research.
"Kami melihat saluran pencernaan
seperti memberikan kesempatan yang
benar-benar unik untuk rumah sistem
baru untuk pengiriman obat dan
penginderaan, dan fundamental untuk
sistem ini adalah bagaimana mereka
bertenaga."
label
stomach
acid,perut,asam lambung,lambung,sensors,voltaic cell,cairan,asam,cairan
asam,acidic fluids,gastrointestinal,batteries,battere, Insinyur
memanfaatkan asam lambung untuk daya sensor kecil
...........................
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Engineers harness stomach acid to power tiny sensors
Ingestible electronic devices could monitor physiological conditions or
deliver drugs
Date:
February
6, 2017
Source:
Massachusetts
Institute of Technology
Summary:
Researchers have designed a small voltaic cell that are
sustained by the acidic fluids in the stomach and generate enough power to run
sensors or drug delivery devices that can reside in the gastrointestinal tract
for extended periods. This type of power could offer a safer and longer-lasting
alternative to the traditional batteries now used to power such devices.
......................
Researchers at MIT and Brigham and
Women's Hospital have designed and demonstrated a small voltaic cell that is
sustained by the acidic fluids in the stomach. The system can generate enough
power to run small sensors or drug delivery devices that can reside in the
gastrointestinal tract for extended periods of time.
This type of power could offer a safer
and lower-cost alternative to the traditional batteries now used to power such
devices, the researchers say.
"We need to come up with ways to
power these ingestible systems for a long time," says Giovanni Traverso, a
research affiliate at the Koch Institute for Integrative Cancer Research.
"We see the GI tract as providing a really unique opportunity to house new
systems for drug delivery and sensing, and fundamental to these systems is how
they are powered."
Traverso, who is also a
gastroenterologist and biomedical engineer at Brigham and Women's Hospital, is
one of the senior authors of the study. The others are Robert Langer, the David
H. Koch Institute Professor at MIT; and Anantha Chandrakasan, head of MIT's
Department of Electrical Engineering and Computer Science and the Vannevar Bush
Professor of Electrical Engineering and Computer Science. MIT postdoc Phillip
Nadeau is the lead author of the paper, which appears in the Feb. 6 issue of Nature
Biomedical Engineering.
Sustained by acid
Traverso and Langer have previously
built and tested many ingestible devices that can be used to sense
physiological conditions such as temperature, heart rate, and breathing rate,
or to deliver drugs to treat diseases such as malaria.
"This work could lead to a new
generation of electronic ingestible pills that could someday enable novel ways
of monitoring patient health and/or treating disease," Langer says.
These devices are usually powered by
small batteries, but conventional batteries self-discharge over time and pose a
possible safety risk. To overcome those disadvantages, Langer and Traverso
worked with Nadeau and Chandrakasan, who specialize in developing low-power
electronics.
The research team took inspiration from
a very simple type of voltaic cell known as a lemon battery, which consists of
two electrodes -- often a galvanized nail and a copper penny -- stuck in a
lemon. The citric acid in the lemon carries a small electric current between
the two electrodes.
To replicate that strategy, the
researchers attached zinc and copper electrodes to the surface of their
ingestible sensor. The zinc emits ions into the acid in the stomach to power
the voltaic circuit, generating enough energy to power a commercial temperature
sensor and a 900-megahertz transmitter.
In tests in pigs, the devices took an
average of six days to travel through the digestive tract. While in the stomach,
the voltaic cell produced enough energy to power a temperature sensor and to
wirelessly transmit the data to a base station located 2 meters away, with a
signal sent every 12 seconds.
Once the device moved into the small
intestine, which is less acidic than the stomach, the cell generated only about
1/100 of what it produced in the stomach. "But there's still power there,
which you could harvest over a longer period of time and use to transmit less
frequent packets of information," Traverso says.
Miniaturization
The current prototype of the device is
a cylinder about 40 millimeters long and 12 millimeters in diameter, but the
researchers anticipate that they could make the capsule about one-third that
size by building a customized integrated circuit that would carry the energy
harvester, transmitter, and a small microprocessor.
"A big challenge in implantable
medical devices involves managing energy generation, conversion, storage, and
utilization. This work allows us to envision new medical devices where the body
itself contributes to energy generation enabling a fully self-sustaining
system," Chandrakasan says.
Once the researchers miniaturize the
device, they anticipate adding other types of sensors and developing it for
applications such as long-term monitoring of vital signs.
"You could have a self-powered
pill that would monitor your vital signs from inside for a couple of weeks, and
you don't even have to think about it. It just sits there making measurements
and transmitting them to your phone," Nadeau says.
Such devices could also be used for
drug delivery. In this study, the researchers demonstrated that they could use
the power generated by the voltaic cell to release drugs encapsulated by a gold
film. This could be useful for situations in which doctors need to try out
different dosages of a drug, such as medication for controlling blood pressure.
Story Source:
Materials provided
by Massachusetts Institute of Technology.
Original written by Anne Trafton. Note: Content may be edited for
style and length.
Journal Reference:
1.
Phillip Nadeau, Dina El-Damak, Dean Glettig, Yong Lin Kong,
Stacy Mo, Cody Cleveland, Lucas Booth, Niclas Roxhed, Robert Langer, Anantha P.
Chandrakasan, Giovanni Traverso. Prolonged energy harvesting for ingestible
devices. Nature Biomedical Engineering,
2017; 1: 0022 DOI:10.1038/s41551-016-0022