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Penelitian baru menyarankan pengobatan  tekanan darah tinggi selama kehamilan

Mengobati tekanan darah tinggi wanita selama kehamilan adalah lebih aman baginya dan aman untuk bayi , sebuah studi baru menunjukkan ....Penelitian ini membahas keyakinan kuno bahwa mengurangi tekanan darah tinggi selama kehamilan dapat mengakibatkan pertumbuhan berkurang dalam kandungan dan kesehatan buruk saat lahir .....read more

New research
recommends treating elevated blood pressure during pregnancy

Date:

January 29, 2015

Source:

Child & Family
Research Institute

Summary:

Treating a woman's
elevated blood pressure during pregnancy is safer for her and safe for the
baby, a new study shows. The study addresses an age-old belief that reducing
elevated blood pressure during pregnancy might lead to reduced growth in the
womb and worse health at birth.

...................

throughout her career in
Canada and the UK, Dr. Laura Magee has taken a restrained approach to use of
blood pressure-lowering medication in her pregnant patients, fearing that
lowering pressure could reduce the flow of blood and vital nutrients to their
babies.

But Magee, a researcher at the Child & Family Research Institute (CFRI)
and the University of British Columbia (UBC), and a physician at BC Women's
Hospital and Health Centre, an agency of the Provincial Health Services
Authority (PHSA), has up-ended her own beliefs with an international study
being published today in the New England Journal of Medicine.

The 15-country study shows that treating a woman's elevated blood pressure
during pregnancy is safer for her, and safe for her baby. As a result of these
findings, Magee and her collaborators recommend normalizing blood pressure in
pregnant women.

"Before this study, I was a 'less tight' controller," Magee says.
"I was hoping that this approach would be better for the baby, without
increasing risks for the mother. However, I was wrong. 'Less tight' control,
which means allowing blood pressure to be mildly to moderately elevated in
pregnancy, is not better for the baby. It's actually harmful to the mother, who
will more often experience levels of blood pressure that increase the risk of
stroke. As a responsible maternity care provider, I can no longer justify a
'less tight' approach to blood pressure control."

The study, which tracked the health of 987 women and their newborns at 94
sites around the world, addresses an age-old belief that reducing elevated
blood pressure during pregnancy might lead to reduced growth in the womb and
worse health at birth.

But normalizing a pregnant women's elevated blood pressure did not result
in poorer outcomes for babies before or after birth. At the same time, allowing
the mother's blood pressure to be mildly to moderately elevated in pregnancy
led to more episodes of dangerously elevated blood pressure that increase the
risk of stroke and death for the mother during pregnancy.

About the study:

·        
The CHIPS Trial (Control of Hypertension in Pregnancy Study) was designed
to study the impact of either 'less tight' or 'tight' control of high blood
pressure during pregnancy on outcomes for the baby and for the mother.

·        
987 women participated between 2009 and 2012 at 94 study sites in 15
countries.

·        
Women participating were between 14 and 33 weeks pregnant. They were
randomly assigned to one of two groups. A group of 497 women had 'less tight'
control with a target diastolic blood pressure of 100 mmHg, while the second
group of 490 women had 'tight' control with a target diastolic blood pressure
of 85 mmHg.

·        
Most of the women in both groups received blood pressure medication at some
point in the trial (77 per cent in the 'less tight' group and 94 per cent in
the 'tight' control group).

·        
The researchers found that the number of babies who died or were admitted
for prolonged newborn intensive care was similar between the two blood pressure
control groups. Fetal growth was also similar.

·        
The study was funded by the Canadian Institutes of Health Research.

Quick facts:

·        
Up to 10 per cent of pregnant women worldwide suffer from hypertension.

·        
All women with hypertension in pregnancy are at increased risk of poor
outcomes for themselves and for their babies. These risks are further increased
when women have hypertension before 34 weeks of pregnancy.

·        
Dr. Magee and study co-author Dr. Peter von Dadelszen received the
prestigious Chesley Award at the 2014 World Congress of the International
Society for Study of Hypertension in Pregnancy.

Quotes:

Dr. Laura Magee, CFRI Senior Clinical Scientist; Physician, BC Women's
Hospital & Health Centre, a PHSA agency; UBC Clinical Professor, General
Internal Medicine: "Our trial showed that you should treat a mother's high
blood pressure in pregnancy. This reduces her risk without increasing the risks
for her baby."

Carl Roy, PHSA President & CEO: "This important finding again
demonstrates why research is so vital to the mandate of the Provincial Health
Services Authority. Our goal is that together with our partners in government,
academia and the scientific community, we can translate findings like these
into even better health care for patients."

Dr. Mark Brown, President, International Society for the Study of Hypertension
in Pregnancy and Professor, University of New South Wales: "For almost 50
years, there has been major controversy over whether it is safe or dangerous to
use blood pressure lowering medications during pregnancy. Following this well
conducted CHIPS study, which is one of a very small number of landmark studies
in this field, we now have an answer: A lower level of blood pressure lessens
the risk of stroke for hypertensive pregnant women without causing any new risk
for baby. This will have a direct impact on the health of pregnant women
worldwide."

Dr. Sandra Lowe, President, International Society of Obstetric Medicine;
Professor, University of New South Wales; Obstetric Physician, Royal Hospital
for Women; lead author of the 2014 Society of Obstetric Medicine of Australia
and New Zealand Guidelines for Management of Hypertensive Disorders of
Pregnancy: "This study has addressed the long standing issue of what blood
pressure targets we should be aiming for in pregnancy to keep both mother and baby
safe. This trial supports that aiming for more "normal" blood
pressure reduced the number of episodes of severe and dangerous maternal
hypertension, with no increase in the rate of complications for their
babies."







Story Source:

The above story is based on materials provided by Child
& Family Research Institute. Note: Materials may be edited for content and length.

http://www.sciencedaily.com/releases/2015/01/150129104324.htm

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