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Penyakit Ginjal Kronis mungkin  Meningkatkan Risiko Tertentu Selama Kehamilan

Di antara perempuan hamil ,hasil  risiko kehamilan - seperti yang merugikan .....seperti kelahiran prematur atau kebutuhan untuk perawatan intensif neonatal - meningkat di tahap penyakit ginjal kronis , sebuah penelitian menyimpulkan ...... Risiko kematian janin atau malformasi intrauterin tidak lebih tinggi pada wanita dengan penyakit ginjal kronis .....read more

Chronic Kidney
Disease May Increase Certain Risks During Pregnancy

Date:

March 12, 2015

Source:

American Society of
Nephrology (ASN)

Summary:

Among pregnant women,
the risk for adverse pregnancy outcomes—such as preterm delivery or the need
for neonatal intensive care—increased across stages of chronic kidney disease,
a study concludes. The risks of intrauterine death or fetal malformations were
not higher in women with chronic kidney disease.

.......................

even mild kidney disease
during pregnancy may increase certain risks in the mother and baby, according
to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN). The findings may be helpful
for guiding prenatal counseling and for monitoring women during pregnancy.

Chronic kidney disease (CKD) is on the rise, and studies suggest that even
early stages of the disease can affect pregnancy outcomes. An Italian research
team led by Giorgina Barbara Piccoli, MD, Rossella Attini, MD, PhD (University
of Torino), and Gianfranca Cabiddu, MD (Azienda Ospedaliera Brotzu) recently
conducted a study -- called the TOCOS (TOrino-Cagliari Observational Study) --
that compared pregnancy outcomes of 504 pregnancies in women with CKD with
outcomes of 836 low-risk pregnancies in women without CKD.

The researchers found that the risk for adverse pregnancy outcomes -- such
as preterm delivery, the need for neonatal intensive care, or the development
of hypertension in the mother -- increased across CKD stages. However, the risk
was not merely linked to reduced kidney function because stage 1 CKD patients
and healthy controls differed significantly, despite the fact that patients
with stage 1 CKD are asymptomatic and have kidney function within the normal
range. The team also found that the risks of intrauterine death or fetal
malformations did not differ between patients and healthy controls.

"The findings indicate that any kidney disease -- even the least
severe, such as a kidney scar form a previous episode of kidney infection, with
normal kidney function -- has to be regarded as relevant in pregnancy, and all
patients should undergo a particularly careful follow-up," said Dr.
Piccoli. "Conversely, we also found that a good outcome was possible in
patients with advanced CKD, who are often discouraged to pursue
pregnancy," she added.

The investigators hope that the new findings may help establish dedicated
programs for the early diagnosis and follow up of pregnancy in CKD. "We
are presently working on a model for 'grading' the risks that will provide
patients and physicians with information when making choices about undergoing
and monitoring pregnancies," said Dr. Piccoli.







Story Source:

The above story is based on materials provided by American Society of Nephrology
(ASN). Note: Materials may be edited for content and length.







Journal Reference:

1.    Giorgina Barbara Piccoli, Gianfranca
Cabiddu, Rossella Attini, Federica Neve Vigotti, Stefania Maxia, Nicola Lepori,
Milena Tuveri, Marco Massidda, Cecilia Marchi, Silvia Mura, Alessandra Coscia, Marilisa
Biolcati, Pietro Gaglioti, Michele Nichelatti, Luciana Pibiri, Giuseppe Chessa,
Antonello Pani, and Tullia Todros.Risk of Adverse Pregnancy Outcomes in
Women with CKD. Journal of the American Society of Nephrology,
March 2015 DOI: 10.1681/ASN.2014050459

http://www.sciencedaily.com/releases/2015/03/150312173530.htm

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