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Reproduksi yang dibantu tidak terkait dengan prestasi akademik yang berkurang pada masa remaja
Analisis US Nationwide di lebih dari 8.000 anak-anak ART tidak menemukan perbedaan dalam nilai tes pendidikan
Date:
June 15, 2015
Source:
European Society of Human Reproduction and Embryology
Summary:
Kinerja akademik oleh anak yang dikandung dengan dibantu teknik reproduksi ( ART / assisted reproduction techniques ) tidak lebih baik atau lebih buruk daripada anak-anak secara spontan dikandung ketika dinilai di kelas sembilan pendidikan sekolah mereka . Demikian pula , lajang ART dan kembar ART juga memiliki skor tes yang sebanding , menunjukkan bahwa , para peneliti mengatakan, ' semakin tinggi risiko obstetrik ' yang diidentifikasi pada kehamilan ART - dan khususnya pada anak kembar - ' . Tidak terkait dengan kinerja akademik yang kurang pada masa remaja '....more
Assisted
reproduction not associated with reduced academic performance in adolescence
US Nationwide analysis of more than 8,000 ART children finds no difference
in educational test scores
Date:
June 15, 2015
Source:
European Society of Human Reproduction and Embryology
Summary:
The academic performance of children conceived by assisted reproduction
techniques (ART) is no better or worse than that of spontaneously conceived
children when assessed at the ninth grade of their school education. Similarly,
ART singletons and ART twins also had comparable test scores, suggesting, say
the investigators, that 'the higher obstetric risk' identified in ART
pregnancies -- and particularly in twins -- 'is not associated with poorer
academic performance in adolescence.'
..................
The academic performance of children conceived by assisted reproduction
techniques (ART) is no better or worse than that of spontaneously conceived
children when assessed at the ninth grade of their school education.(1)
Similarly, ART singletons and ART twins also had comparable test scores,
suggesting, say the investigators, that "the higher obstetric risk"
identified in ART pregnancies -- and particularly in twins -- "is not
associated with poorer academic performance in adolescence." (2)
"These findings are very important for infertile patients," they
add.
Details of the study are reported today at the Annual Meeting of ESHRE by
Anne Lærke Spangmose Pedersen, a medical student in the fertility clinic of
Copenhagen University Hospital Hvidovre, Denmark. She noted that so far only
few studies have explored IQ in ART children, and no previous studies have
included ninth grade test scores in a complete national cohort of
15-16-year-old adolescents all conceived by ART.
This, however, was a substantial national study involving every child
conceived by ART and born in Denmark between 1995 and 2000, a total of 8251
children born as 4991 singletons and 3260 twins. These children were then
compared to two control populations of children -- the first comprising all
twins born in Denmark during the same period (a total of 10,833) and a randomly
selected group of spontaneously conceived singletons (total 10.052).
The study effectively compared the academic performance of all four groups
according to results of a general test of academic performance which all ninth
grade students in Denmark (at age 15-16 years) complete. The test grades
academic performance from -3 to +12, with average scores of 7. The system of
national records and registries in Denmark with demographic and epidemiological
data make such studies possible.
Initial results did show some discrepancies between the groups, but
following statistical adjustments maternal age, birth weight, gestational age
and social status, the differences disappeared. For example, ART singletons
achieved a higher mean test score than spontaneously conceived singletons (7.71
and 6.75 respectively, p<0,001), but this difference did not persist after
the statistical adjustments.
"We were pleased to see the results," said Ms Pedersen. "The
higher rate of twins and preterm birth in ART singletons might have given rise
to lower academic test scores. But our results now confirm smaller studies
which have shown no difference in IQ between ART and non-ART children. All our
four study groups had test scores very close to the average, which is
reassuring -- and shows the high validity of the study."
With so many children in some countries now conceived by assisted
reproduction (as many as 5% in Denmark), Ms Pedersen described the results as
"reassuring" for both parents and IVF clinics. Any possible effect of
prematurity in ART children, she said, seems to be removed over time.
She added that these results from a national cohort study are likely to be
similar in other populations, although Denmark itself had a lower twin rate
than many other countries between 1995 and 2000. And multiple pregnancies, she
explained, remain a safety concern in ART.
"ART is still associated with a slightly increased risk of congenital
malformations and prematurity," said Ms Pedersen, "and we should
continue to survey our ART children, as new developments in technique -- such
as vitrification and blastocyst culture -- are always being introduced. Any
effect of these methods has not yet been ruled out. So it is of great
importance that we accept the responsibility to find out."
In the meantime, however, Ms Pedersen said the results of this study in
terms of academic development were sufficiently strong to have important public
health implications, and "might finally persuade politicians and society
as a whole that there is no reason for caution in future ART generations. Thus,
we can continue to perform ART as a safe and sound method from the long-term
child perspective."
Notes
1. Ninth grade usually refers to the ninth year of education after
kindergarten, with students usually aged around 15 years. Some educators stress
the pivotal importance of this year in shaping future directions.
2. Several studies have suggested that obstetric outcomes in pregnancies
after ART are worse than those seen after spontaneous conception, a trend
usually attributed to the higher proportion of multiple pregnancies in ART (and
as a result prematurity and low birthweight). However, there have been studies
(though generally with conflicting results) showing an increased risk of
preterm delivery and low birthweight even in singleton pregnancies conceived by
ART.
Story Source:
The above post is reprinted from materials provided byEuropean
Society of Human Reproduction and Embryology. Note:
Materials may be edited for content and length.