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Masalah kognitif yang umum setelah serangan jantung

Setengah dari semua pasien yang bertahan dari serangan  jantung mengalami masalah penangkapan dengan fungsi kognitif seperti memori dan perhatian , sebuah studi internasional menunjukkan . Anehnya , bagaimanapun , kelompok kontrol yang terdiri dari pasien serangan jantung memiliki sebagian besar tingkat masalah yang sama  . Hal ini menunjukkan bahwa tidak hanya serangan jantung dan  akibat kurangnya  oksigen ke otak yang merupakan penyebab kesulitan pasien ....read more

Cognitive
problems are common after cardiac arrest

Date:

April 17, 2015

Source:

Lund University

Summary:

Half of all patients
who survive a cardiac arrest experience problems with cognitive functions such
as memory and attention, a major international study shows. Surprisingly,
however, a control group comprising heart attack patients had largely the same
level of problems. This suggests that it is not only the cardiac arrest and the
consequent lack of oxygen to the brain that is the cause of the patients’
difficulties.

.....................

half of all patients who
survive a cardiac arrest experience problems with cognitive functions such as
memory and attention. This has been shown by a major international study led
from Lund University. Surprisingly, however, a control group comprising heart attack
patients had largely the same level of problems. This suggests that it is not
only the cardiac arrest and the consequent lack of oxygen to the brain that is
the cause of the patients' difficulties.

The study led by Lund University involved 950 cardiac arrest patients in
Europe and Australia. Six months after the cardiac arrest, half of the patients
had died, and the survivors were followed up with cognitive screening tests.
Both the patients and their relatives were also asked to report changes that had
taken place following the cardiac arrest.

Almost 300 cardiac arrest survivors also underwent more detailed tests.
Their results were compared with a control group made up of heart attack
patients.

"We thought there would be a clear difference between the groups,
because the heart attack patients had not been exposed to any oxygen deficiency
in the brain. However, they had signs of mild brain damage to almost the same
extent as the cardiac arrest patients," says Dr Tobias Cronberg, Associate
Professor at Lund University and consultant neurologist at Skåne University
Hospital in Lund.

The researchers therefore believe that the cognitive problems can be
explained to a high degree by the risk factors that are common to patients with
different types of heart complaint, for example diabetes, high blood pressure
and high cholesterol. Other studies have already shown that these factors
increase the risk of dementia.

"Our conclusion is that if we are to provide good treatment to cardiac
arrest patients, we don't just need to save their lives; we also need to ensure
that they tackle these risk factors, for example through improved diet and more
exercise. Otherwise they are at risk of developing dementia," says Tobias
Cronberg.

Dr Cronberg believes it would be good if all cardiac arrest patients
received follow-up not just with regard to physical health, but also with
regard to memory and attention. Both patients and their relatives have
appreciated the opportunity to discuss any deterioration, its causes and how it
can be addressed.

However, the international study showed that the quality of life of most
cardiac arrest survivors was generally in line with that of the rest of the
population. According to Tobias Cronberg, survival in itself probably plays an
important part in this: the patients know that they have come close to dying
and are grateful to still be alive.

The main aim of the study was to compare the effect of a body temperature
of 33°C and 36°C following cardiac arrest. The researchers have previously
shown that maintaining a temperature of 36°C produced the same survival rate as
cooling to 33°C.

"We have now also demonstrated that not only survival but also
cognitive ability is the same in patients who have been kept at 33°C or 36°C.
This is very important for the reliability of the results we have previously
presented," said Tobias Cronberg.

The research group's results have been published in two journals, Circulation andJAMA
Neurology.







Story Source:

The above story is based on materials provided by Lund University. Note: Materials may be edited
for content and length.







Journal References:

1.    Tobias Cronberg, Gisela Lilja, Janneke
Horn, Jesper Kjaergaard, Matt P. Wise, Tommaso Pellis, Jan Hovdenes, Yvan
Gasche, Anders Åneman, Pascal Stammet, David Erlinge, Hans Friberg, Christian
Hassager, Michael Kuiper, Michael Wanscher, Frank Bosch, Julius Cranshaw,
Gian-Reto Kleger, Stefan Persson, Johan Undén, Andrew Walden, Per Winkel, Jørn
Wetterslev, Niklas Nielsen.Neurologic Function and Health-Related Quality of
Life in Patients Following Targeted Temperature Management at 33°C vs 36°C
After Out-of-Hospital Cardiac Arrest. JAMA Neurology, 2015;
DOI:10.1001/jamaneurol.2015.0169

2.    G. Lilja, N. Nielsen, H. Friberg, J.
Horn, J. Kjaergaard, F. Nilsson, T. Pellis, J. Wetterslev, M. P. Wise, F.
Bosch, J. Bro-Jeppesen, I. Brunetti, A. F. Buratti, C. Hassager, C. Hofgren, A.
Insorsi, M. Kuiper, A. Martini, N. Palmer, M. Rundgren, C. Rylander, A. van der
Veen, M. Wanscher, H. Watkins, T. Cronberg. Cognitive Function in
Survivors of Out-of-Hospital Cardiac Arrest After Target Temperature Management
at 33 C Versus 36 C. Circulation, 2015; 131 (15):
1340 DOI: 10.1161/CIRCULATIONAHA.114.014414

http://www.sciencedaily.com/releases/2015/04/150417085222.htm

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