Skor rendah pada tes memori dan berpikir mungkin sinyal Alzheimer 18 tahun sebelum terkena penyakit--T-REC-komunitas reptil-semarang--KSE-komunitas satwa eksotik

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Skor rendah pada tes memori dan berpikir mungkin sinyal Alzheimer 18 tahun sebelum terkena penyakit

Date:

June 25, 2015

Source:

American Academy of Neurology (AAN)

Summary:

Errors on memory and thinking tests may signal Alzheimer's up to 18 years before the disease can be diagnosed, a new study suggests.

Sebuah studi menunjukkan ,Kesalahan pada tes memori dan  berpikir mungkin sinyal Alzheimer hingga 18 tahun sebelum penyakit dapat didiagnosis

............. " Perubahan dalam berpikir dan memori yang mendahului gejala yang jelas dari penyakit Alzheimer dimulai pada dekade sebelumnya, " kata penulis studi Kumar B. Rajan , PhD , di  Rush University Medical Center di Chicago . " Meskipun kami saat ini tidak dapat  mendeteksi perubahan tersebut pada individu yang berisiko , kami mampu mengamati mereka di antara sekelompok orang yang akhirnya berkembang ke demensia akibat Alzheimer . " ....more

Low scores on
memory and thinking tests may signal Alzheimer's 18 years prior to disease

Date:

June 25, 2015

Source:

American Academy of Neurology (AAN)

Summary:

Errors on memory and thinking tests may signal Alzheimer's up to 18 years
before the disease can be diagnosed, a new study suggests.

............................

A new study suggests that errors on memory and thinking tests may signal
Alzheimer's up to 18 years before the disease can be diagnosed. The research is
published in the June 24, 2015, online issue of Neurology®, the medical journal of the American Academy of
Neurology.

"The changes in thinking and memory that precede obvious symptoms of
Alzheimer's disease begin decades before," said study author Kumar B.
Rajan, PhD, with Rush University Medical Center in Chicago. "While we
cannot currently detect such changes in individuals at risk, we were able to
observe them among a group of individuals who eventually developed dementia due
to Alzheimer's."

For the study, 2,125 European-American and African-American people from
Chicago with an average age of 73 without Alzheimer's disease were given tests
of memory and thinking skills every three years for 18 years.

Twenty-three percent of African-Americans and 17 percent of
European-Americans developed Alzheimer's disease during the study. Those who
scored lower overall on the memory and thinking tests had an increased risk of
developing the disease. During the first year of the study, people with lower
test scores were about 10 times more likely to be diagnosed with Alzheimer's
disease than people with higher scores, with the odds increasing by 10 for
every standard deviation that the score was lower than the average.

Based on tests completed 13 to 18 years before the final assessments took
place, one unit lower in performance of the standardized cognitive test score
was associated with an 85 percent greater risk (relative risk of 1.85) of
future dementia. "While that risk is lower than the same one unit lower
performance when measured in the year before dementia assessment, the
observation that lower test scores 13 to 18 years later indicates how subtle
declines in cognitive function affect future risk," said Rajan.

"A general current concept is that in development of Alzheimer's
disease, certain physical and biologic changes precede memory and thinking
impairment. If this is so, then these underlying processes may have a very long
duration. Efforts to successfully prevent the disease may well require a better
understanding of these processes near middle age," Rajan said.







Story Source:

The above post is reprinted from materials provided byAmerican
Academy of Neurology (AAN). Note: Materials may be edited
for content and length.







Journal Reference:

1.   
K. B. Rajan, R. S. Wilson, J. Weuve, L. L. Barnes, D. A. Evans. Cognitive
impairment 18 years before clinical diagnosis of Alzheimer disease dementia. Neurology,
2015; DOI: 10.1212/WNL.0000000000001774

http://www.sciencedaily.com/releases/2015/06/150625143929.htm

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