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A ' Hearty ' Eater : kondisi Makanan yang besar pada hati se ekor ular 

Date:

March 9, 2005

Source:

National Science Foundation

Summary:

Se ekor python Burma yang kuat , tetapi apakah itu model untuk “human exercise” ? Menurut sebuah artikel yang diterbitkan dalam edisi 3 Maret di jurnal Nature , kebiasaan makan ular membuat model utama  bagi kebugaran kardiovaskular .

............ Tidak seperti hati manusia , yang memiliki dua ventrikel atau bilik memompa  , hati reptil hanya  memiliki satu .

" Pada mamalia , termasuk manusia , peningkatan 10-30 persen massa ventrikel dapat terjadi setelah beberapa minggu dan  bulan pelatihan aerobik  yang intens, " kata Hicks ....more

A 'Hearty' Eater: Big Meals Condition A Snake’s Heart

Date:

March 9, 2005

Source:

National Science Foundation

Summary:

A Burmese python is strong, but is it a
model for human exercise? According an article published in the March 3 issue
of the journal Nature, the snake’s eating habits make it a prime model of
cardiovascular fitness.

...................

A Burmese python is strong, but is it a
model for human exercise? According an article published in the March 3 issue
of the journal Nature, the snake’s eating habits make it a prime model of
cardiovascular fitness. The heart has the amazing ability to adapt to altered
physiological requirements, and, according to the authors, this cold-blooded
snake may provide insights into how remodeling of the heart occurs in adapting
to prolonged exercise and in response to some diseases.

The python does not eat frequently; it’s
more of a binge eater. James Hicks at the University of California, Irvine,
together with his colleagues, discovered the snake's tell-tale heart undergoes
drastic physiological changes after the reptile consumes a large meal. Hicks
observed that the snake’s oxygen consumption increased seven-fold within 24 to
48 hours after eating. This heightened metabolic state lasted for up to seven
days and was accompanied by a rapid remodeling of the ventricle--the lower
portion of the blood-pumping organ. In experiments, the python’s ventricle
increased in mass by 40 percent within 48 hours.

Unlike a human heart, which has two
ventricles or pumping chambers, a reptile heart has only one.

“In mammals, including humans, a 10-30
percent increase in ventricular mass can occur following several weeks to
months of intense aerobic training,” said Hicks.

In the snake, the rapid ventricular
growth coincided with an increased production of the muscle protein, myosin.
Myosin is involved in muscle contraction, and hence, plays a key role in
pumping blood.

Hicks and his colleagues propose that
these animals could be an informative model for investigating fundamental mechanisms
leading to cardiac remodeling and ventricular growth in other animals,
including humans.

Hicks’ research is supported by the
Integrative Organismal Biology program at the National Science Foundation.







Story Source:

The above post is reprinted from materials provided byNational Science Foundation. Note: Materials may be edited for content and length.

http://www.sciencedaily.com/releases/2005/03/050307215725.htm

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