“Bitting back” : Snake venom yang mengandung faktor pembekuan beracun--T-REC-komunitas reptil-semarang--KSE-komunitas satwa eksotik

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“Bitting back” : Snake venom  yang mengandung faktor pembekuan beracun

Date:

February 27, 2013

Source:

BioMed Central Limited

Summary:

Racun kuat dari saw-scaled viper Echis carinatus mengandung antikoagulan dan koagulan menurut sebuah studi baru . Ini mungkin menjadi sumber obat ampuh untuk mengobati penyakit manusia .  The saw-scaled viper famili Echis, yang bertanggung jawab untuk sebagian besar serangan ular pada manusia , yang dikenali oleh suara ' mendesis '  mereka . Racun Echis menyebabkan koagulopati , yang dapat mengakibatkan gejala mulai dari kurangnya pembekuan darah , perdarahan , gagal ginjal dan stroke

................ The saw-scaled viper family Echis , yang bertanggung jawab untuk sebagian besar serangan ular pada manusia , yang dikenali oleh suara  ' mendesis '  mereka,,...more

Biting back:
Snake venom contains toxic clotting factors

Date:

February 27, 2013

Source:

BioMed Central Limited

Summary:

The powerful venom of the saw-scaled viper Echis carinatus contains both
anticoagulants and coagulants according to a new study. These may be a source
of potent drugs to treat human disease. The saw-scaled viper family Echis,
responsible for most snake attacks on humans, are recognizable by the
‘sizzling’ noise they make, produced by rubbing together special serrated
scales, when threatened. Echis venom causes coagulopathy, which can result in
symptoms ranging from lack of blood clotting, hemorrhage, renal failure and
stroke.

................

The powerful venom of the saw-scaled viper Echis carinatus contains both
anticoagulants and coagulants finds a study published in the launch edition of
BioMed Central's open access journalJournal of Venomous
Animals and Toxins including Tropical Diseases (JVATiTD). These may be a
source of potent drugs to treat human disease.

The saw-scaled viper family Echis, responsible for most snake attacks on
humans, are recognizable by the 'sizzling' noise they make, produced by rubbing
together special serrated scales, when threatened. Echis venom causes
coagulopathy, which can result in symptoms ranging from lack of blood clotting,
hemorrhage, renal failure and stroke.

Researchers from the Razi Vaccine and Serum Research Institute, Iran led by
Hossein Zolfagharian noted that treating plasma with venom from Echis carinatus
actually causes it to coagulate. Splitting the venom by ion exchange
chromatography showed that then venom contained both coagulants and
anticoagulants. The clotting factors alone were toxic to mice.

The diametric effects of snake venom on blood are of interest because of
medical applications, and although snakes can be considered as dangerous to
humans -- they may yet save lives.

In the auspicious Year of the Snake, BioMed Central, the open access
publisher, is pleased to announce that the Journal of Venomous Animals and
Toxins including Tropical Diseases (JVATiTD), the official academic journal of
the The Center for the Study of Venoms and Venomous Animals (CEVAP) of São
Paulo State University (UNESP), based in Brazil, has moved to BioMed Central's
open access publishing platform. Also this journal marks growth of BioMed
Central's portfolio of open access journals to 250.

Along with research into snakes JVATiTD publishes studies into all aspects
of toxins, venomous animals, and their derivative products, as well as tropical
diseases especially infectious diseases, parasites and immunology.







Story Source:

The above post is reprinted from materials provided
by BioMed Central Limited. Note:
Materials may be edited for content and length.







Journal Reference:

1.   
Hossein Salmanizadeh, Mahdi Babaie and Hossein Zolfagharian. In
vivo evaluation of homeostatic effects of Echis carinatus snake venom in Iran. Journal
of Venomous Animals and Toxins including Tropical Diseases, 2013, 19:3
DOI: 10.1186/1678-9199-19-3

http://www.sciencedaily.com/releases/2013/02/130226193845.htm

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