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Mencegah cerebral palsy pada bayi prematur melalui pemantauan dermal

Date:

September 29, 2015

Source:

Kobe University

Summary:

Sebuah metode potensial skrining untuk penyakit kuning ( hiperbilirubinemia ) , penyebab cerebral palsy dan kehilangan pendengaran pada bayi prematur dengan kyperbilirubinemia , telah diusulkan dengan menggunakan monitoring kulit tanpa rasa sakit . Kelompok riset juga menentukan area kulit yang benar  untuk memantau hasil yang akurat . Penelitian ini telah memperluas kemungkinan metode yang akurat dari pemantauan penyakit kuning , dan diharapkan ini akan menyebabkan kerugian penurunan cerebral palsy dan pendengaran pada bayi prematur karena kyperbilirubinemia .

......... Jepang memiliki tingkat kelangsungan hidup tertinggi di dunia untuk bayi prematur , berkat perawatan medis canggih dan ketersediaan Unit Perawatan Intensif Neonatal ( NICU ) . Meskipun demikian , kasus cerebral palsy dan gangguan pendengaran yang disebabkan oleh penyakit kuning neonatal terus terjadi , dengan kasus yang dilaporkan selama minimal 2 dalam setiap 1000 bayi yang lahir sebelum minggu ke-30 kehamilan ........more

Preventing
cerebral palsy in preterm infants through dermal monitoring

Date:

September 29, 2015

Source:

Kobe University

Summary:

A potential method of screening for jaundice (hyperbilirubinemia), a cause
of cerebral palsy and loss of hearing in preterm infants with
kyperbilirubinemia, has been proposed using painless dermal monitoring. The
research group also determined the correct area of skin to monitor for accurate
results. This study has expanded the possibilities for accurate methods of
monitoring jaundice, and it is hoped that this will lead to a decrease in
cerebral palsy and hearing loss in preterm infants due to kyperbilirubinemia.

.........................

A research group led by Kobe University Graduate School of Medicine Project
Professor MORIOKA Ichirou and Professor IIJIMA Kazumoto (Department of
Pediatrics) has suggested a potential method of screening for jaundice
(hyperbilirubinemia), a cause of cerebral palsy and loss of hearing in preterm
infants with kyperbilirubinemia, using painless dermal monitoring. The group
also determined the correct area of skin to monitor for accurate results. This
study has expanded the possibilities for accurate methods of monitoring
jaundice, and it is hoped that this will lead to a decrease in cerebral palsy
and hearing loss in preterm infants due to kyperbilirubinemia. The results of
this research were published on 23rd September 2015 in the online version of The Journal of Pediatrics.

Japan has the world's highest survival rate for preterm infants, thanks to
advanced medical treatment and the availability of Neonatal Intensive Care
Units (NICU). Despite this, cases of cerebral palsy and hearing loss caused by
neonatal jaundice continue to occur, with cases reported for at least 2 in
every 1000 infants born before the 30th week of gestation. It has also been
established that cases of jaundice can worsen even two weeks after birth,
meaning that there is a need for continuous long-term monitoring of infants in
the NICU. However, jaundice in preterm infants is difficult to detect through
physical observation, and monitoring through a daily blood test is not a
realistic option.

Professor Morioka's research group focused on transcutaneous jaundice
monitoring used in daily health tests for full term infants. They monitored the
bilirubin levels of 85 infants with a birth weight of under 1500 grams in NICUs
at Kobe University, Kakogawa City Hospital, Hyogo Prefectural Kobe Children's
Hospital, Japanese Red Cross Society Himeji Hospital, and Takatsuki General
Hospital. The research group took a total of 383 measurements. Through their
results they were able to ascertain that the chest and back areas of preterm
infants have the highest levels of sensitivity, and bilirubin levels in those
areas were close to bilirubin levels in the blood.

In addition to expanding the possibilities for transcutaneous monitoring of
jaundice in preterm infants, they discovered the optimum area of skin to
monitor. This means that neonatal jaundice levels can now be monitored
continuously using a painless method over a long period of time. It is hoped
that this discovery will contribute to a decrease in cerebral palsy and hearing
loss in preterm infants. Project Professor Morioka stated, "Even among
paediatricians, many assume that neonatal jaundice is no longer an issue, but
there are still many unknown factors regarding the effects of the illness on
developing brain cells. I want to prevent after-effects such as cerebral palsy
and hearing loss by providing effective jaundice monitoring for preterm
infants."







Story Source:

The above post is reprinted from materials provided by Kobe
University. Note: Materials may be edited for content and length.







Journal Reference:

1.   
Daisuke Kurokawa, Hajime Nakamura, Tomoyuki Yokota, Sota Iwatani, Takeshi
Morisawa, Yoshinori Katayama, Hitomi Sakai, Tomoaki Ioroi, Kazumoto Iijima,
Ichiro Morioka.Screening for Hyperbilirubinemia in Japanese Very Low
Birthweight Infants Using Transcutaneous Bilirubinometry. The
Journal of Pediatrics, 2015; DOI:10.1016/j.jpeds.2015.08.038

http://www.sciencedaily.com/releases/2015/09/150929070228.htm

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